BPC 157

(Body Protection Compound 157)

OVERVIEW:

BPC 157 is a naturally occurring peptide (basically a short protein).

Early research is suggesting that it may have muscle and wound healing effects. Studies also show potential benefits for the gut, organs, muscle and even the brain.

This article was created to provide a deep dive into the potential benefits of supplementing with BPC 157.

 

CONTENTS

(Touch to Navigate)


WHAT IS BPC 157?

BENEFITS OF BPC 157

HOW TO TAKE BPC 157

BPC 157 FAQ

WHAT IS BPC 157?

In this section we are going to look at what BPC 157 actually is and how it works.

BPC 157 IN A SNAPSHOT:

IS A FORM OF:
- Nootropic
- Anti-infammatory

PRIMARY FUNCTION:
- Anti-inflammation and healing

OTHER FUNCTIONS:
- Cognitive Function and Brain Health
- Gut Health

OTHER NAMES:
- PL14736
- PL-10
-BEPECIN

WHAT THE EXPERTS HAVE
TO SAY

WHAT IS BPC 157?

BPC is a  naturally occurring protein found in stomach acid that was first discovered in the 1990s. BPC 157 is a peptide chain made of 15 amino acids that is synthetically produced based on the natural BPC found in the body [1].

HOW DOES BPC 157 WORK?

BPC 157 is believed to benefit muscle and tendon healing by triggering the formation of new blood vessels – a process called angiogenesis (by increasing VEGF). 

This is why it is often used for its regenerative potential in particular it’s in helping heal wounds, cuts, and other types of damage in the body [4, 5].

A big interest currently being investigated is in helping with IBD. Because of it’s ability to increase new blood vessels it may have benefits in speeding up the recovery of an inflamed gut which is usually notoriously slow. [6].

It’s also believed that BPC 157 may promote wound and tendon healing by blocking the growth-inhibiting effects of a specific molecule (called 4‐hydroxynonenal) [7].

In terms of helping to heal tendons (which some people are beginning to use it for) 

It might do this by causing tendon cells to make more receptors for growth signalling molecules. 

What does this mean?

Basically, it allows tendon cells to grow and move more freely when repairing from an injury and therefore speeding up the healing process. [8, 9].

BPC 157 is also believed to have anti inflammatory effects which is also believed to be what is contributing to it’s wound, ulcer and tissue healing effects. [10, 11].

BPC 157  is also being shown to improve the activity of neurotransmitters like serotonin and dopamine. Which may have benefits for depression, seizures, pain, and may even promote gut health (because serotonin is used for gut transit). More research is needed to understand exactly how BPC 157 works in the brain [12, 13, 14, 3].

Finally,  BPC 157 can increase the production of nitric oxide (NO), which has benefits for the heart, circulation and blood pressure (by balancing it) and may also help with reducing high potassium levels [15, 16].

 

BPC 157 BENEFITS

In this section we are going to dive deep into the potential benefits of BPC 157.

POTENTIAL BENEFITS OF BPC 157 - SNAPSHOT

May promote muscle and tendon healing

May protect organs from toxins and damage

May reduce inflammation

May Benefit Inflammatory Bowel Disease (IBD)

May help in healing burns, cuts and broken bones

May protect the brain and nervous system

May help in healing stomach ulcers

May help in reversing the damage of NSAIDs

May help
with pain

May help with balancing blood pressure


POTENTIAL BENEFITS OF BPC 157 - IN DEPTH

 

Muscle and Tendon Healing:

In rats with Achilles tendon injuries, BPC 157 helped the tendons to heal almost completely, compared to control which did not make a full recovery [7, 5, 20].

Similarly, BPC 157 improved muscle healing for rats whose muscles had been injured. [21, 22, 23].

 

Organ Toxins and Damage:

BPC 157 might be useful in counteracting drug intoxication.

In rats, BPC 157 helped decreased the negative effects of amphetamines by helping counteract the chemical imbalances they can trigger, especially on the dopamine system [43, 44].

 

Inflammatory Bowel Disease (IBD):

Perhaps one of the more powerful potential benefits of BPC 157 is its benefits for IBD. 

Both anecdotal and early clinical trials suggest BPC 157 as being safe and effective for helping with IBD. [6, 17, 18].

In rats with IBS, BPC 157 helped with reducing inflammation [6, 11, 19].

 

 

Burns, cuts and broken bones:

In studies using mice with burns, creams containing BPC 157 helped speed up the healing process, even when also given corticosteroids (which are known to slow healing) [24, 25, 26].

Other studies on mice and rats with cuts saw an improvement in healing when given BPC 157. It was even effective in diabetic rats, which is promising because diabetes can slow the process of wound healing [27, 28].

Injections with the peptide also spurred the healing of broken bones in rabbits [29].

 

Brain and nervous system:

BPC may have benefits for those suffering a traumatic brain injury. 

In studies of rats with a traumatic brain injury that were given BPC 157 injections had less brain damage [30].

In a study on rats with nerve damage in their legs, BPC 157 injections helped the nerve cells regrow and heal [31].

BPC 157 was also shown to protect mice from drug-induced seizures [32].

BPC 157 may also have a positive effect on mood. In one study, BPC 157 decreased depression-like behaviour in rats. Comparable to that of conventional antidepressants [33].

 

 

Stomach ulcers:

In rats with stomach ulcers BPC 157 appeared to help heal the ulcer. It also protected the rats’ intestines from alcohol damage [32, 34, 35, 36, 11, 37, 11].

 

 

NSAIDs Damage:

NSAIDs (non-steroidal anti-inflammatory drugs) like aspirin and ibuprofen.Can cause damage to organs like the stomach and liver if taken in high doses [39, 40].

BPC 157, either injected or consumed in drinking water, reversed these toxic effects in rats given NSAIDs [40, 41, 42, 38].

 

 

Pain:

BPC 157 may be a mild painkiller. Rats injected with the peptide experienced less pain to pinching and similar unpleasant stimuli. [45].

 

 

Blood pressure:

BPC 157 is believed to have a blood stabilizing effect in that it can either help bring blood pressure up or down. For example in one study on rats with high blood pressure BPC 157 reduced blood pressure, and in rats with abnormally low blood pressure BPC 157 increased blood pressure. [15].

 

 

 

TAKING BPC 157

In this section we are going to look at the best approaches to taking BPC 157.

 

How to take BPC 157:

BPC 157 can either be taken via injection or orally. Until very recently injection was the only viable and effective way of gaining the benefits of BPC 157.

However recent advancements have occurred in delivery which allow BPC 157 to be just as effective when taken orally. In fact, taking BPC 157 orally may be more beneficial for the gut than injection.

The form of BPC 157 that has shown to be most effective orally is an arginine based BPC 157 called Pentadecapeptide. 

In fact it’s the exact form of BPC 157 we use in our flagship gut healing product as well as in our injury healing product.

 

 

When do you take BPC 157?

BPC 157 can be taken at any time of the day. It may also be effective when taken after exercise or training to speed up recovery.

 

 

How long does it take for BPC 157 to work?

A lot of people wonder how long it takes for BPC 157 to start working. The truth is that like most supplements results vary from person to person. However, typical improvements will usually be seen within 2 weeks to 1 month of regular use.

 

 

Where to buy BPC 157?

It can be fairly difficult to source high-quality BPC 157. However, here at LVLUP health we now stock it in the highest quality orally available form. 

 

 

How much BPC 157 should I take?

There are no definite BPC 157 dosing recommendations currently available. However, we have based our dosing on the current research available. With dosing of 500mcg per serving.

 

 

BPC 157 With or Without Food?

BPC 157 can be taken with or without food.

 

 

Injectable VS Oral BPC 157?

As we have previously mentioned BPC 157 initially only worked when injected. However, BPC 157 is now equally as effective when taken orally thanks to recent breakthroughs in oral delivery [60], [61]

 

BPC 157 FAQ

In this section, we are going to take a look at how TUDCA is being shown to benefit chronic diseases.

Is BPC 157 safe?

Yes, studies done on oral BPC 157 show it to be safe. [60,61,62,63

Of course, there have been no studies done on long term use. However, we do not believe in taking BPC 157 long term anyway. Most people only need to take it short term for specific reasons i.e injury and gut healing.

 

Is BPC 157 legal within Australia?

 

Yes BPC 157 like most peptides is legal within Australia as long as you’re over the age of 18.

 

 

Is BPC 157 systemic?

Yes, when taken orally BPC 157 works systemically.

 

 

Is BPC 157 FDA approved?

No like most supplements BPC 157 is not FDA approved.

 

 

Is BPC 157 a steroid?

No BPC 157 is peptide, not a steroid.

 

 

Does BPC 157 build muscle?

Taking BPC 157 won’t increase muscle size alone. However it does speed up healing which means you will be able to train longer and harder which in turn will lead to an increase in muscle size.

 

CONCLUSION

BPC 157 is a powerful peptide that may have far-reaching benefits for the gut, brain and body. As research on this peptide continues it will likely uncover more understanding of how this peptide may be used for human health.

If you’re interested in trying BPC 157 you may be interested in our gut product and our performance product.

YOU MAY BE INTERESTED IN OUR BPC 157 PRODUCTS