TUDCA

500mg. 60 capsules, 30 servings per bottle.

Used for centuries in Chinese medicine. TUDCA is a potent bile salt that helps improve bile flow and has been shown to have potential far reaching benefits for liver and whole body health. 

$69.95

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TUDCA is a bile acid and has a horrible taste and smell; this is normal and is a sign of supplemental purity. 

NO this TUDCA is NOT made from bear bile. It is a synthetic compound that is manufactured using a very precise process.

This process was developed and has been used in Japan since 1954 and is just as powerful if not more powerful than it’s original source (bear bile).

We do not and will never condone the use of bears in the manufacturing of this product.

Our TUDCA is 100% Vegan. And is free from dairy, gluten, fillers and preservatives.

There are a lot of shady TUDCA products out there. We believe in quality and purity which is why we are completely open and transparent.

You can see proof of our quality here in our certificate of analysis.

AT A GLANCE
BENEFITS
DOSING
RESEARCH
HANDOUT

Benefits

Supports Liver Function

Supports Digestion & Gut Health

Supports Cellular Health

TUDCA at A Glance

What is TUDCA?

Tauro-Urso-Deoxy-Cholic Acid or much easier to say; TUDCA
is a bile acid that has been used for centuries in Chinese Medicine to treat liver related issues.
It also has high notoriety in the Bodybuilding world as a powerful PCT supplement.

Recent studies are showing far reaching benefits for the liver and whole body health.

TUDCA plays an important role in digestion, in particular the digestion of fats.* It has also been shown to have promising benefits of the liver, by improving bile flow and bile duct integrity.*

It may also assist in improving cellular health by improving the degradation of cellular waste within the mitochondria and cell membrane.* In the gut it may assist with improving microbiome diversity.*

And may provide neuro-protective benefits in neuro-degenerative diseases such as ALS,  Alzheimers, Parkinsons and Huntingtons disease.*

Benefits Breakdown

Liver Support

The liver plays a huge role in your overall health and plays a major part in some of the most important functions in the body.

Including detoxification of harmful chemicals and microbes from your food and environment, immunity, hormone processing, digestion and even blood sugar control.

Therefore having a healthy liver is vitally important to overall health. Unfortuntely our modern lifestyle and dietary choices take a big toll on the liver.

Fortunetly through diet, life style and supplements we can dramatically improve the function and health of our livers. And TUDCA is a supplement that can have a dramatic benefit on the liver by helping improve bile flow and bile duct integrity.* Both of which are crucial in a healthy and well functioning liver.

Digestion Support

 
Many people now suffering from gut related issues such as digestive discomfort, acid reflux, leaky gut and absorption issues. Fixing gut health and digestion is multifacited approach and there is no one product or lifestyle choice that will fix everything. However using products that support digestion and the microbiome play a huge role in fixing the gut.
 
And TUDCA can be a great way to improve digestion, in particular the digestion of fats. Bile is critical in the break down of fats so if your bile flow is poor or you have had your gall bladder removed then you are going to have a hard time breaking down fats as well as other nutrients from your food.  TUDCA may assist with this by helping to improve bile flow and bile duct integrity and therefore improving your fat digestion and nutrient absorption, especially fat soluable vitamins A, D, E, K  as well as omega fatty acids.
 
TUDCA may also assist with improving microbiome health via improved bile which is critical for destroying harmful bacteria.*

Cellular Health

 

The integrity and health of your cells is vitally important to your overall all health. And one of the most important factors in celluar health is your mitochondria, which are essentially the powerhouses of your cells.

And since the liver is responsible for so many processes it requires a lot of energy and therefore a lot of mitochondria. And it has been shown that TUDCA actually helps to protect the mitochondria in your cells by reducing the release of a molecule called BAX entering the mitochondria and causing it’s early death. Therefore improving mitochondria levels and function within the liver which can lead to an improvement in your overall health.*

 
 

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Dosing Intructions


Dosage:

 

Studies suggest taking anywhere between 250mg – 1500mg.

We suggest taking 1 capsule per day.

Each capsule is 250mg and there are 60 capsules in a bottle. 

 

When to take:

You can take TUDCA whenever you like.

However we suggest taking it a night for maximum benefit.
It can also be taken before fatty meals to improve digestion


Side Effects?

There are no known side effects of taking TUDCA, occasionaly some people may encounter ‘detox symptoms’ or ‘Herxhiemer reaction’ such as tiredness or cold and flu like symptoms. These are just part of your bodies healing and should surpass in a few days or week. 

 

Taste and Smell

TUDCA has a very potent Acetone-like smell and horrible taste.  This is because TUDCA is a bile acid and we do not use excipients or fillers in our products. The smell and taste being so strong is indicative of the purity and quality of the product and is nothing to be concerned about; this taste is why we encapsulate it, but the smell is unavoidable!  

RESEARCH

1. Bodewes, F., Wouthuyzen-Bakker, M., Bijvelds, M., Havinga, R., de Jonge, H., & Verkade, H. (2012). Ursodeoxycholate modulates bile flow and bile salt pool independently from the cystic fibrosis transmembrane regulator (Cftr) in mice. American Journal Of Physiology-Gastrointestinal And Liver Physiology, 302(9), G1035-G1042. doi: 10.1152/ajpgi.00258.2011

2. Invernizzi, P., Setchell, K. D., Crosignani, A., Battezzati, P. M., Larghi, A.,
O’Connell, N. C., & Podda, M. (1999). Differences in the metabolism and disposition of ursodeoxycholic acid and of its taurine-conjugatedspecies in patients with primary biliary cirrhosis. Hepatology (Baltimore, Md.), 29(2), 320–327. https://doi.org/10.1002/hep.510290220

3.  Larghi, A.,Crosignani, A., Battezzati, P. M., De Valle, G., Allocca, M.,Invernizzi, P., Zuin, M., & Podda, M. (1997). Ursodeoxycholic and tauro ursodeoxycholic acids for the treatment of primary biliary cirrhosis: a pilot crossover study. A limentary pharmacology & therapeutics, 11(2), 409–414. https://doi.org/10.1046/j.1365-2036.1997.124295000.x

4.  Panella, C.,Ierardi, E., De Marco, M. F., Barone, M., Guglielmi, F. W., Polimeno, L., & Francavilla, A. (1995). Does tauroursodeoxycholic acid (TUDCA)
treatment increase hepatocyte proliferation in patients with chronic liver disease?. The Italian journal of gastroenterology, 27(5), 256–258.

5.  Laukens, D., Devisscher, L., Van den Bossche, L., Hindryckx, P., Vandenbroucke, R. E., Vandewynckel, Y. P., Cuvelier, C., Brinkman, B. M., Libert, C.,
Vandenabeele, P., & De Vos, M. (2014). Tauroursodeoxycholic acid inhibits experimental colitis by preventing early intestinal epithelial cell death. Laboratory investigation; a journal of technical methods and pathology, 94(12), 1419–1430. https://doi.org/10.1038/labinvest.2014.117

6. Yoon, Y. M., Kim, S., Han, Y. S., Yun, C. W., Lee, J. H., Noh, H., & Lee, S. H.
(2019). TUDCA-treated chronic kidney disease-derived hMSCs improve
therapeutic efficacy in ischemic disease via PrPC. Redox biology, 22, 101144. https://doi.org/10.1016/j.redox.2019.101144

7. Vettorazzi, J. F., Ribeiro, R. A., Borck, P. C., Branco, R. C., Soriano, S., Merino, B., Boschero, A. C., Nadal, A., Quesada, I., & Carneiro, E. M. (2016).
The bile acid TUDCA increases glucose-induced insulin secretion via the cAMP/PKA pathway in pancreatic beta cells.  Metabolism: clinical and experimental, 65(3), 54–63. https://doi.org/10.1016/j.metabol.2015.10.021

8. Yoon, Y. M., Kim,
S., Han, Y. S., Yun, C. W., Lee, J. H., Noh, H., & Lee, S. H.
(2019). TUDCA-treated chronic kidney disease-derived hMSCs improve
therapeutic efficacy in ischemic disease via PrPC. Redox biology, 22, 101144. https://doi.org/10.1016/j.redox.2019.101144

9. Castro-Caldas, M., Carvalho, A. N., Rodrigues, E., Henderson, C. J., Wolf, C. R.,Rodrigues, C. M., & Gama, M. J. (2012). Tauroursodeoxycholic acid prevents MPTP-induced dopaminergic cell death in a mouse model of Parkinson’s disease. Molecular neurobiology, 46(2), 475–486. https://doi.org/10.1007/s12035-012-8295-4

10.  Piazza, F., Montagnani, M., Russo, C., Azzaroli, F., Aldini, R., Roda, E., & Roda, A. (2000). Competition in liver transport between chenodeoxycholic
acid and ursodeoxycholic acid as a mechanism for ursodeoxycholic acid and its amidates’ protection of liver damage induced by chenodeoxycholic acid. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 32(4), 318–328. https://doi.org/10.1016/s1590-8658(00)80025-0

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.